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1-800-RxKings

$20 COUPON FOR FIRST TIME INFERTILITY ORDERS OVER $400

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KINGS carries one of the largest inventories of Fertility medications in the New York area.

Follistim™ 
Humegon 
Fertinex™  
Repronex 75 
Progesterone Capsules & Suppositories 
Crinone® 
Lupron 
Pregnyl 
Profasi 
Serophene/Clomid 
Diagnostic Tests 

Email: info@kingsrx.com

INFERTILITY INFO

1-800-RxKings 

1-800-(795-4647)

Ten percent to 15 percent of couples are infertile, defined as the inability to become pregnant after 1 year of frequent, unprotected sexual intercourse. Infertility is not the same thing as sterility – the inability to conceive a child under any circumstance. Often, a diagnosis of infertility simply means that becoming pregnant is a challenge – but this challenge can be dramatically aided by medical treatment.

Causes

Every month, a substance called follicle-stimulating hormone (FSH) is secreted by a woman’s pituitary gland, signaling the ovaries to mature an egg follicle (a fluid filled capsule). When one or sometimes two of these follicles have reached a mature size, the pituitary gland releases another substance called lutenizing hormone (LH). LH carries the message for the "lead follicle" – or biggest follicle – to release its egg. The egg then travels to the fallopian tube. For pregnancy to occur, sperm must unite with the egg in the fallopian tube.

However, for a significant number of couples attempting to get pregnant, something goes wrong in the process of ovulation and fertilization. Infertility can result from a reproductive abnormality in the man, the woman, or both. Fifty percent to 70 percent of the time, the woman is the infertile partner. Ovulation disorders, including irregular or absent menstrual periods due to hormonal deficiencies or imbalances, are frequently the cause of female infertility.

Causes of male infertility include low sperm count, poor sperm motility (movement), inability of sperm to penetrate the egg, vasectomy reversals and duct (vas deferens) obstructions.

Treatments    

Fertility drugs are the primary treatment for women who are infertile due to ovulation disorders. These medications use different mechanisms to regulate or induce ovulation. In general, they exert actions designed to work like natural FSH and LH.

Current fertility medications include:

Clomiphene citrate – Usually used to regulate ovulation in women who have irregular menstrual periods. It causes the pituitary gland to release more FSH and LH, which stimulates the growth of an egg follicle.

Human menopausal gonadotropin (hMG) – Most often prescribed for women who do not ovulate on their own. Unlike clomiphene, which stimulates the pituitary gland, hMG and other gonadotropins directly stimulate the ovaries

Human chorionic gonadotropin (hCG) – Used in combination with clomiphene, hMG and FSH, it stimulates the "lead follicle," or the biggest follicle, to release its egg.

FSH – Commonly prescribed for women who have elevated levels of natural LH, an imbalance often due to polycystic ovarian syndrome. FSH is essentially hMG without the LH. Like hMG, it works by stimulating the ovaries to mature egg follicles.

GnRH – Used in women whose hypothalmus does not properly release the natural hormone GnRH, which stimulates the pituitary gland’s release of FSH and LH. GnRH is administered in a pattern that mimics the natural rhythm.

GnRH analogs – Used to treat women with irregular ovulatory cycles who ovulate prematurely (before the lead follicle is mature enough) during hMG treatment. GnRH analogs deliver constant GnRH to the pituitary gland, which alters hormone production so a physician can induce follicle growth with hMG.

Bromocriptine – Used to treat women whose ovulation cycles are irregular due to elevated levels of prolactin, the hormone that stimulates milk production in new mothers. It inhibits prolactin production.

Fertility drugs are occasionally responsible for multiple births. While clomiphene citrate only rarely results in pregnancy with more than twins, hMG and FSH carry a greater risk of causing multiple births. About 15 percent to 25 percent of hMG and FSH treatment cycles result in multiple pregnancies – about two-thirds being twins and one-third being triplets or more. As a rule, the greater the number of fetuses, the higher the risk of premature labor. Babies born prematurely are at increased risk for a number of medical and developmental problems. Some steps are available to reduce the risk of multiple pregnancies. If a woman requires an hCG injection to trigger ovulation, and ultrasound exams show that too many follicles have developed, she and her physician can decide to withhold the hCG injection. However, for many couples, the desire to become pregnant overrides concerns about conceiving multiple babies.

If too many babies are conceived, the removal of one or more fetuses (multifetal pregnancy reduction) can offer improved survival odds for the strongest fetuses. However, this presents serious emotional and ethical challenges for many people. Couples considering fertility drug treatment should discuss this possibility with their doctors before starting therapy.

Some studies have suggested a link between fertility drugs and an increased, long-term risk of developing ovarian cancer. However, in 1998, a large study showed no association between fertility drugs and ovarian cancer. Research is ongoing on this issue. This also may be an important topic to discuss with your doctor before initiating treatment with fertility drugs.

Assisted reproductive technologies (ARTs) offer another option for treating infertility in both women and men.

The most widely known ART for female infertility is in vitro fertilization in which an egg is retrieved from the woman’s ovary, fertilized in the laboratory, and implanted as an embryo in her uterus. In the United States, in vitro techniques consistently have led to pregnancy rates in the range of 25 percent for each time eggs are retrieved from a woman.

Unlike other male infertility treatments that emphasize increasing the quantity or quality of sperm, ICSI works with individual sperm. With ICSI, a single sperm is drawn into a microscopic needle. This individual sperm is then injected directly into the egg, dramatically improving the likelihood of fertilization.

Other ARTs and related techniques currently in use include:

Gamete (egg and sperm) intrafallopian transfer (GIFT)

Sperm and embryo freezing and storage

Electroejaculation/microsurgical epididymal sperm aspiration

 

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